UCLA OHRPP IRB Submissions

OHRPP IRB Submissions

The Office of Human Research Protection Programs supports two internet-based software applications to support the submission, review, and approval of research projects involving human subjects:

  1.  webIRB 
    1. New submissions not currently supported in BruinIRB
    2. Amendment/Continuing Review-Closure/ PARs for active and previously approved submissions in webIRB
  2. BruinIRB
    1. UCLA relying on another IRB*
    2. Humanitarian Use Devices (HUD)
    3. Emergency Use
    4. Expanded Access
    5. Right to Try applications

All NEW UCLA relying on another IRB, Emergency Use, HUD, Expanded Access, and Right to Try applications must be submitted in BruinIRB.    

*Effective January 25, 2023, all NEW Industry-sponsored, multi-site FDA-regulated research conducted at UCLA must use a single IRB, per the June 2023, UCLA Policy Board (HRPB) determination.  Accordingly, investigators must identify an external IRB (e.g. Advarra or WCG) that will serve as Reviewing IRB for these research studies.  Investigators must submit a request to cede review to an external IRB in BRUIN IRB.

Both applications are designed to branch in response to information provided about the study procedures. Each system requires an account that uses the single sign-on UCLA Logon ID credentials. Both applications function as a document repository, providing study personnel with easy access to study documents like approved consent forms.

Submission requirements for amendments, continuing review, and post-approval monitoring reports will differ for studies approved by an external IRB, including clinical studies approved by a commercial IRB.  Review the IRB Reliance Policy and the FAQs for the Commercial IRB Review  for additional information.

  • All users must have a webIRB account to log into webIRB. Please visit the “How to get a webIRB account” page for instructions.
  • Access BruinIRB Accounts page for instructions on how to request an account for BruinIRB.

For general questions, contact the OHRPP's main phone numbers (310) 825-5344 for the Medical IRB or (310) 825-7122 for the General Campus IRB. For questions specific to the webIRB application, email webIRBHelp@research.ucla.edu. Questions related to BruinIRB should be directed to BruinIRB@research.ucla.edu. Please be sure to describe the nature of your question. 

Before your study begins, you must have IRB approval. Below are the CTSI partner site IRB submission tools:

IRB Contacts for Partner Sites

Cedars-Sinai – click here to go to the Cedars-Sinai Webridge IRB system. For more information, contact:

Office of Research Compliance and Quality Improvement
Cedars-Sinai Medical Center
8383 Wilshire Blvd., Suite 742
Beverly Hills, CA 90211
Phone: (310) 423-3783
Email: irb@cshs.org

Charles R. Drew University – Click here for more information on the IRB for Charles R. Drew University. If you have any questions regarding the IRB functions and review process, contact:

Office for the Protection of Human Subjects
Charles R. Drew University of Medicine and Science
1731 East 120th Street, Building F
Los Angeles, CA 90059
Phone: (323) 563-5990
Email: irb@cdrewu.edu

Junko Nishitani, CDU IRB Director
(323) 563-5990

Lundquist/Harbor-UCLA – Click here to go to the iRIS IRB System. You will need to log-in. For more information, contact:

Office of Compliance and Regulatory Affairs
Lundquist/Harbor-UCLA Medical Center
1124 West Carson St
Torrance, CA 90502
Phone: (310) 222-3624

View Lundquist/Harbor-UCLA workflow

UCLA – The online Institutional Review Board application system, webIRB, is available to all UCLA Investigators and Study Staff. For questions or assistance, contact:

Office of the Human Research Protection Program (OHRPP)
10889 Wilshire Blvd, Suite 830
Los Angeles, CA 90095-1406
Campus Mail Code: 140648

Email: North & South General Institutional Review Boards (GC-IRB)
Email: The Medical Institutional Review Boards 1,2, & 3 (M-IRB)

Training sessions are being held on the South campus and in the Kinross Building. Click here to schedule a training session.

To subscribe to the webIRB listserv: Send an e-mail to: webIRB-subscribe@lists.ucla.edu
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