Human Subjects / IRB Process

Mandatory Online CITI Training for Key Personnel

All UCLA key personnel conducting human research are required to complete human subjects protection training through an online program called the Collaborative Institutional Training Initiative (CITI). Review the FAQs About CITI Training for registration instructions and training details. Sign up to complete the UCLA Human Subjects Protection training. You can also enroll in the Good Clinical Practice and Responsible Conduct in Research courses, but these courses are optional for most people. 

If you have questions, please read the IRB Training Requirements or check with your supervisor.

Learn at Lunch and Noontime Education Series

OHRPP offers two types of hour-long training sessions for UCLA research staff and faculty: Learn at Lunch and Noontime Education Series. Please subscribe to investigators-l-subscribe@lists.ucla.edu for announcements for upcoming sessions.

WebIRB Training

The OHRPP offers hands-on webIRB training. You will learn and practice common tasks related to submitting and managing studies in the webIRB system.

Privacy and Confidentiality Education and Training

HIPAA information can be found on ResearchGo. Please contact the Privacy Office at 310-206-3874 with questions about privacy issues and the Office of Compliance Services with questions about HIPAA training.

Additional Training Resources

Customized OHRPP classes and presentations are available on a range of topics to fit your needs. To schedule a training or presentation:

• Call or e-mail the Director or Associate Director to discuss your needs.
• Use the Human Research Training Request Form to request a presentation tailored to your needs.
• Schedule individual appointments. See OHRPP Staff Consults for details.
• For general IRB education, requests and assistance, please send an e-mail inquiry to: OHRPPEQI@research.ucla.edu

NIH Clinical Trials & Human Subjects Requirements & Guidelines

The UCLA Clinical and Translational Science Institute (CTSI) Grants Submission Unit (GSU) has put together a number of tools and resources to clarify the requirements for NIH applications regarding human subjects and clinical trial policies. These resources reflect changes in FORMS-H, which are effective for applications due on or after January 25, 2023, and are meant to help guide you through the requirements, based on the type of studies you are proposing within your application.

OHRPP IRB Submissions

The Office of Human Research Protection Programs supports two internet-based software applications to support the submission, review, and approval of research projects involving human subjects:

1.  webIRB 
   
   1. Amendment/Continuing Review-Closure/ PARs for active and previously approved submissions in webIRB that have not been migrated to BruinIRB.
2. BruinIRB
   
   1. All new studies must be submitted in BruinIRB as of September 9, 2025.  See BruinIRB Deployment FAQs for more information.
   2. If you have received a notice that your approved webIRB study has been migrated to BruinIRB, all future amendments, continuing reviews and PARs must be submitted in BruinIRB.  

Please forward any questions or concerns to BruinIRB@research.ucla.edu or consult the BruinIRB Resource Library for quick guides, training videos, and other information.

*Effective January 25, 2023, all NEW Industry-sponsored, multi-site FDA-regulated research conducted at UCLA must use a single IRB, per the June 2023, UCLA Policy Board (HRPB) determination.  Accordingly, investigators must identify an external IRB (e.g. Advarra or WCG) that will serve as Reviewing IRB for these research studies.  Investigators must submit a request to cede review to an external IRB in BRUIN IRB.

Both applications are designed to branch in response to information provided about the study procedures. Each system requires an account that uses the single sign-on UCLA Logon ID credentials. Both applications function as a document repository, providing study personnel with easy access to study documents like approved consent forms.

NOTE:
Submission requirements for amendments, continuing review, and post-approval monitoring reports will differ for studies approved by an external IRB, including clinical studies approved by a commercial IRB.  Review the IRB Reliance Policy and the FAQs for the Commercial IRB Review  for additional information.

• All users must have a webIRB account to log into webIRB. Please visit the “How to get a webIRB account” page for instructions.
• Access BruinIRB Accounts page for instructions on how to request an account for BruinIRB.

For general questions, contact the OHRPP's main phone numbers (310) 825-5344 for the Medical IRB or (310) 825-7122 for the General Campus IRB. For questions specific to the webIRB application, email webIRBHelp@research.ucla.edu. Questions related to BruinIRB should be directed to BruinIRB@research.ucla.edu. Please be sure to describe the nature of your question.